Skip Ribbon Commands
Skip to main content


When a woman's body no longer makes estrogen, hormone therapy may be an option. But, hormone therapy (HT), in which estrogen and progestin (a synthetic progesterone) are used in combination, has been controversial over the years.

To learn more about women's health, and specifically hormone therapy, the National Institutes of Health (NIH) did a study called the Women's Health Initiative (WHI) beginning in 1991. The study involved more than 161,000 generally healthy postmenopausal women.